Hexyl 450 KL

Hexyl 450 KL is characterized by powerful anabolic and androgenic properties, which is why it is recommended exclusively for men for sports purposes. For women, the threat is androgenic side effect (virilization), expressed by symptoms of coarsening of the voice, increased aggression, and others.

Details

Transparent oily solution, light yellow to yellow in color, with a characteristic odor.

Hexyl 450 is a composite testosterone product (mix) containing a calibrated mixture of short and long-acting esters, which provides the most even and prolonged action of the steroid (up to 2-3 weeks).

1 ml of solution contains active substances: 450 mg/ml

• testosterone acetate 30 mg;
• testosterone propionate 73 mg;
• testosterone phenylpropionate 73 mg;
• testosterone cypionate 125 mg;
• testosterone decanoate 147 mg;

– auxiliary substances: benzyl alcohol, peach or peanut oil.

Pharmacodynamics

Hexyl is composed of five testosterone esters (acetate, propionate, phenylpropionate, cypionate and decanoate). Testosterone is the primary androgen hormone synthesized and released by the testicles. It is responsible for the growth and development of male sexual organs and secondary sexual characteristics (maturation of the prostate, seminal vesicles, penis and scrotum), male hair distribution (face, pubis, chest), laryngeal development, body muscles and fat distribution. Retains nitrogen, sodium, potassium and phosphorus, increases anabolism and reduces protein catabolism. Premature increase in plasma of testosterone concentration in the prepubertal period causes the epiphyses to close and the growth to stop. Stimulates the production of erythropoietin and erythrocytes. Through a feedback mechanism, it inhibits the secretion of pituitary luteinizing and folliculostimulating hormones and causes the suppression of spermatogenesis.

In women it inhibits pituitary gonadrophic function, ovarian function, mammary glands, endometrial atrophy. Due to its antagonistic action against estrogen, it is used in the treatment of uterine fibroids, endometriosis, breast cancer. Manifests beneficial action in the climacteric period.

The effect of Hexyl 450 cycle for an athlete is a powerful anabolic, androgenic, even anti-catabolic. Throughout the cycle, this mix effectively contributes to building muscle mass and prevents its destruction, which explains its popularity. However, it’s action is not limited to this: endurance and working capacity also develop, potential strength increases, fatigue decreases, the function of joints, ligaments and bones is strengthened and improved, the appetite and libido are strengthened. Testosterone has a wide spectrum of action, due to which it is relevant for almost any physical sports, including bodybuilding.

Pharmacokinetics

The testosterone esters in this preparation have different absorption and elimination rates, which ensures a fast and prolonged effect (up to 4 weeks) after a single administration: testosterone propionate and acetate acts for the first 24 hours. Testosterone phenylpropionate and cypionate begin to act over 24 hours after administration and last up to 2 weeks. Testosterone decanoate is the slowest after the onset of action, but with the longest duration. In the blood, about 98% of testosterone binds to a specific fraction of globulins, which binds testosterone and estradiol. Biotransformation occurs in the liver to various 17-ketosteroids, which after conjugation with glucuronic or sulfuric acid are excreted in the urine (approximately 90%). Approximately 6% of the absorbed preparation is excreted in the faeces in free form.

Uses

Deep intramuscular. Hexyl dosage recommended for athletes 450 mg per week on average. Because this drug is long-acting and high dosed, intensive injection is not required, however, for a smooth background of action, rotate the injection site in order to avoid soreness and inflamation.

Benefits

Increases the effectiveness of anticoagulants and antidiabetics (dose adjustment is required), inhibits the elimination of cyclosporine. Inducers of liver enzymes (barbiturates, rifampicin, carbamazepine, phenylbutazone, phenytoin) reduce the effect of testosterone.

Due to the specificity of the effect, Hexyl 450 is used mainly in bulking cycles. It is a powerful enough anabolic steroid to be used in solo, but for maximum progress it is combined with other effective drugs

Side Effects

Probable side effects: aggression, sweating, acne, suppression of testosterone production, water retention, gynecomastia and some others, due to increased androgenic or estrogenic activity. This steroid is highly aromattized, so in a heavy cycle there may be a need for taking an antiestrogen, such as Anastrozole.

Individual hypersensitivity to the drug, prostate or breast cancer; prostate hyperplasia with symptoms of urinary disorders; nephrosis or nephrotic phase of nephritis, edema; hypercalcemia; liver function disorders; diabetes; heart or coronary insufficiency, a history of myocardial infarction, atherosclerosis in elderly men; pregnancy, lactation.

In acute overdose the toxicity of testosterone is quite low. In chronic overdose it is possible to develop priapism. In this case it is necessary to stop the administration of this drug, and after the disappearance of symptoms – to resume treatment in lower doses.